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ABSTRACT
 
Background & aim: Nowadays, sedentary lifestyle has amplified health problems, such as an increased incidence of cardiovascular disease. This study examined the influence of eight weeks of combined training and garlic supplementation on changes in adiponectin and lipid in inactive boys.
 
Methods: In the present quasi-experimental study, 46 disabled boys were purposefully and voluntarily chosen to participate in research and were then randomly divided into four groups of supplement (n = 10), exercise + placebo (n = 13), exercise + supplement (n = 13) and control (n = 10). Fasting blood samples were taken after 8 to 10 hours, 24 hours before the start of practice and 48 hours after the last training session. Data were analyzed using the KS test, t-test, ANOVA and LSD test.
 
Results: Comparison between groups showed a statistically significant difference in level of adiponectin (p =0.01), triglycerides (p =0.03) and LDL-C (p =0.01). A significant difference at triglyceride levels between the control group and exercise + supplement (p=0.02), exercise + placebo and supplement (p=0.04) and exercise + placebo controls (p=0.01) were seen. Also, a significant difference at levels of HDL-C amonge groups exercise + supplementation and exercise + placebo (p=0.01), exercise + supplement and Control (p=0.01), exercise + placebo controls (p=0.01) and complementary and control (p=0.01) was observed respectively.
 
Conclusion: It seems that taking garlic supplements along with combination exercise can be one of the non-pharmacological methods to improve the level of adiponectin and lipid profile and effective in reducing cardiovascular risks.