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Background & aim: Testis is an important organ of the male reproductive system and its structure could be influenced by diabetes. Aloe Vera has a hypoglycemic effect thus, the present study evaluates the effect of Aloe Vera on the testis tissue of a 20-day embryo of rat born from a diabetic mother. Methods: Thirty female Sprague Dawley rats were randomly divided into three groups, subsequently two groups were injected with streptozotocin (50 mg/kg/IP) and the males were placed next to female rats in a separate cage in order to mate. One group of rats received aloe vera extract (400 mg/kg), orally, in gestational age during while others were giving distilled water. After 20 days, rats were sacrificed and their embryos were removed and fixed by 10% formalin. The embryos were processed and embeded in paraffin. Five µm sections were made and stained by hematoxyline- eosin and cellular alteration of testis was evaluated. Data were analyzed using one-way ANOVA. Results: Mean of body weight, seminiferous tubules diameter, spermatogonia numbers, leydig cells and sertoli cells were significantly different in all groups (p<0.05). Conclusion: The present study demonstrated that Aloe Vera extract can increase the spermatogonium, Leydig and Sertoli cells in diabetic rats.

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Background & aim: Physical training accompanied with herbal supplement consumption is one of the proposed methods for controlling obesity and its complications, such as diabetes, insulin resistance and inflammation of the liver. The purpose of this study was to evaluate the effect of 10 weeks of aerobic exercise and supplementation of green tea on lipid profile, insulin resistance and liver enzymes (GGT, ALT, AST) in obese diabetic women (type 2). Materials and Methods: A total of 46 diabetic obese women aged between 45 - 60 were randomly divided into four groups of green tea, aerobic exercises with green tea, aerobic training (12), and placebo group (10 people) respectively. Groups of participants supplement were given a capsule of 1500mg green tea extract daily for 10 weeks. The exercises were followed three sessions a week in a ten week period. Results: At the end of week 10, in the supplements group, exercise plus supplementation and exercise the levels of fasting blood sugar, triglycerides, total cholesterol, low-density lipoprotein were reduced, but this reduction was not significant (p>0.05). However, green tea and exercise was significantly increased the low-density lipoprotein (P≤ 0.05). A significant reduction was seen on the Low-density lipoprotein, HOMA, insulin and weight (P≤ 0.05). Exercise and supplementation significantly decreased the serum levels of liver enzymes in the experimental group (P≤ 0.05). Conclusions: Green tea supplements with aerobic training were effective in controlling obesity and type 2 diabetes. By increasing the duration of the exercise and supplementation, it may find desirable results on serum cholesterol and triglycerides.