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introdaction & aim: Magnesium playes an important role in the structure and cell metabolism. In this research , anti oxidant effects of magnesium sulfate against oxidative stress effects of was investigated Methods: In this experimewtal study 36 male adults rats were placed into4 groups, with nine rats in each group. Treatment was then carried out as follows. Group I received olive oil (intraperitoneally) and distilled water (intragastrically), and served as the untreated control animal group. Group II was the hepatotoxicity group that was given a suspension of (i.p., 0.5 mL/kg b.wt, 50% in olive oil), twice a week. Groups III received dissolved in distilled water daily via an intragastric tube(.0.15M g/kg b.wt.)Groups IV were the treatment group that received dissolved in distilled water daily, via an intragastric tube 0.15 g/kg b.wt.),with (i.p., 0.5 mL/kg b.wt., 50% in olive oil) twice a week. After a 28-day treatment period, the animals were deprived of food overnight, anesthetized by exposure to diethyl ether, and then sacrificed by decapitation. Blood ws collected from the jugular vein, and serum was separated and used for liver marker assays. Levels of ALT, AST ALP and GGT were estimated using commercial kits. The liver homogenates were used for the assay of SOD .All data were expressed as means S.E.M. Statistical analysis was carried out using one-way ANOVA followed by a Tukey post hoc test. The criterion for statistical significance was p<0.05. Results:In the -treated control group, serum ALT, AST, ALP and GGT were significantly increased as compared with the untreated control group. In contrast, the group that also received mgso4 Showed signifi cantlyless elevated levels of ALT, AST, ALP and GGT. compared to normal levels. Liver SOD activity in -treated rats was decreased significantly when compared with the the control group. Treatment with protected this enzyme activity. Conclusion:The results of this study showed that magnesium sulfate has improved oxidative effect of in the liver rats because of its antioxidant properties.

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Abstract                  
Background & aim: Social anxiety, also known as social phobia, is one of the most common psychiatric disorders in the society, which, due to the complex and multidimensional nature of this disorder, requires the planning and implementation of appropriate treatment. The aim of this study was to determine the effectiveness of Wells meta-cognitive therapy in group therapy on meta-cognitive beliefs of female students with social anxiety disorder.
 
Methods: the present quasi-experimental study was carried out using a pre-test one-month post-test and control group. The statistical population of the present study were female undergraduate students of Azad University, Payam Noor University, and Applied Sciences University in Gachsaran, Iran. The study was conducted on 300 students using Social Anxiety Inventory(SPI). The cut point was 40 with the accuracy of 80% and cut point of 50 with the accuracy of 89%, distinguished people with social anxiety from non-specific individuals. At that point, sixty participants were randomly selected and randomly assigned to experimental and control groups of 30 participants each. The MCQ-30 metacognitive beliefs questionnaire was performed in three stages: pre-test, post-test and one-month follow up for the groups. After carrying out ethical considerations(informed consent, willingness, secrecy), the experimental group received metacognitive therapy during the ten sessions and the control group received no treatment. The obtained results were analyzed using descriptive statistics and multivariate covariance analysis(MANCOVA) using SPSS software version 21.
 
Result: Mean and standard deviation of metacognitive beliefs in pretest; experimental group 08, 89, 26, 6, control group 90.22, 5.58, posttest 70.04, 4.66, control group 84.63, 6.79 and follow-up in experimental group 71.38, 6.79 and control group 85.74, 6.94. Furthermore, the results of analysis of covariance indicated that there was a significant difference between the two groups in all                        post-tests(p<0.05). According to the descriptive indices, the experimental group's post-test scores were significantly lower than the control group. This was also the case for the components of follow-up research, therefore group metacognitive therapy significantly improved the metacognitive beliefs of patients with social anxiety at post-test and the consistency of treatment outcomes at follow-up.
 
Conclusion: Results showed improvement in patients' symptoms after one month post-test and follow-up. According to the post-test results, it appeared that meta-cognitive group therapy was effective in improving metacognitive beliefs in patients with social phobia disorder.