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Showing 2 results for Nazeri
I Nazari, M Mohammadi , G Nazeri , Volume 19, Issue 4 (7-2014)
Abstract
Background & aim: Among the problems affecting the mental health of war veterans is post traumatic stress disorder. The aim of the present study was to investigate the effectiveness of Gestalt therapy on post traumatic stress disorder (PTSD) symptoms on veterans of Yasuj city, Iran.
Methods: The research design was based on pre-post test study with control group and a three month followed-up. The research population included veterans who were referred to Salman hospital and had been diagnosed of having PTSD. The sample included 24 veterans with PTSD which were randomly selected and divided into two groups of experimental and control (n=12). The Post Traumatic Stress Disorder Mississippi Scale (M-PTSD) administered before training for both groups was used to assess symptoms of PTSD. The experimental group was exposed to Gestalt therapy interventions in six, 90 minute weekly sessions. Both groups were conducted measurements after the first, third, fifth and seventh therapy sessions. The data were analyzed using ANCOVA.
Results: The results in the post-test stage revealed that Psychological Debriefing and behavioral interventions reduced PTSD symptoms (p<0.01), as well as, the results in followed up stage revealed that Psychological Debriefing and behavioral interventions reduced PTSD symptoms (p<0.05).
Conclusion: Gestalt therapy technique can be used as a standard in conjunction with other treatments which can be used to improve the symptoms of post-traumatic stress disorder.
Zh Nazeri Givi, Kh Onsory, E Moslemi , Volume 22, Issue 6 (2-2018)
Abstract
Abstract
Background and Aim: Cervical cancer is the fourth most common cancer that is the first cause of mortality among women in the world and the seventh rank among all cancers. One of the risk factors for cervical cancer is infection with the papilloma virus. On the other hand, microRNAs have been suggested as new markers for cervical cancer diagnosis. Meanwhile, microRNA129-2 is a cellular proliferation inhibitor and an invertebrate cellular agent. The aim of this study was to evaluate the expression of microRNA129-2 in women with papilloma virus infected cervical cancer and compare it with women with cervical cancer without infection with papilloma virus and healthy group.
Methods: In this semi-experimental study, 20 paraffin tissue samples from women with papilloma virus infected cervical cancer, 20 samples of paraffin tissue from women with cervical cancer without infection of the papilloma virus and 20 samples of normal pap smear from Mirzakochek Khan Hospital The forest was collected in Tehran in 1394. After de-paraffinization, extraction of RNA was performed and expression of miR129-2 was investigated using Real Time PCR method among the groups. Data was analyzed using Grafpad prism6 software.
Results: According to the results a significant decrease was seen in the expression of this gene in infected patients compared to control group (p = 0.0004). Also, expression of miR129-2 in infected tissues of papilloma viruses was reduced in comparison with non-contaminated cancerous tissues (p = 0.0001). Although this decrease in expression was observed between the patients without infection with the papilloma virus and the control group, it was not statistically significant (p = 0.083). There was no significant relationship between expression of miR129-2 with age (p = 0.99) and grade of disease (p = 0.39).
Conclusion: Considering the reduced expression of miR129-2 in cancerous samples, the expression of miR129-2 expression can be considered as a valuable initial diagnostic agent and it plays an important role in determining the prognosis of cervical cancer.
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