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Showing 15 results for Fathi
Ms Enayati , A Heidarei , M Malekzadeh, Y Abolfathi, Volume 11, Issue 1 (4-2006)
Abstract
ABSTRACT:
Introduction & Objective: Self-inflicted burn is a violent method of suicide. Since our society faces lots of psychological, social, personal and economical problems due to self-inflicted burn, more survey for this event can assist us to know its causes and prevent from its occurrence. This research was carried out to compare general health, self- esteem and social support in patient's self-inflicted burn and non-self-inflicted burn of the Choromy accidental and burning hospital in Ganaveh.
Materials & Methods: This is a descriptive – analytic study. The sample consisted of 60 inpatients burnt (males & females) of the Choromy accidental and burning hospital (Ganaveh). The method of sampling was simple random. Participants completed the General Health Questionnaire (G.H.Q- 28) of Goldberg, Cooper Smith’s questionnaire of self–esteem and Philip’s social support scale. Multivariate analysis of variance (MANOVA) and T-test were the major statistical analysis in this research.
Results: The mean and standard deviation of the general health were 44.57 ± 14.65 for self-inflicted burn persons and for non - self inflicted burn they were 10.83 ± 6.27. In the self–esteem variable, the mean and the standard deviation were 57.90 ± 4.94 for self-inflicted burn persons and 55.47 ± 6.04 for non-self inflicted burn ones. Mean and standard deviation of whole social supporting were 20.40 ± 4.94 for self-inflicted burn persons and 23.73 ± 1.17 for non-self inflicted burn group. The findings showed significant differences between the two groups from viewpoint of general health and social supporting while there were no significant differences between two groups in case of self–esteem.
Conclusion: There are a significant relationship between general health, social supporting and self-inflicted burn.Therefore, in order to prevent self inflicted burn it is suggested that we make a relationship between persons and societies, families, groups and different institutes.
S Pouyan Majd , V Dabidi Roshan, R Fathi, Volume 19, Issue 6 (9-2014)
Abstract
Background & aim: Obesity and asthma, are cardiorespiratory changes that could affect the airways and may play a role in occurrence of symptoms during exercise. However, there is little information about the effect of high and low humidity on cardiorespiratory factor in obese children with asthma during progressive aerobic activity.
Methods: The present case-control study was carried out with ten obese asthmatic children and fifteen healthy children who performed an exercise protocol in different environments (relative humidity 65 ± 5% versus 35 ± 5%). During exercise, cardiorespiratory parameters were controlled using K4B2. Heart rate, systolic blood pressure and double product were measured with a digital sphygmomanometer and stethoscope polar. Data were analyzed with dependent T test and ANOVA with repeated measures analysis.
Results: A significant increase was detected in the markers of HR, SP and DP after exercise in obese children with asthma and healthy children (P< 0.005). However, indexes of cardiorespiratory and exhaustion was significantly higher in obese children with asthma and healthy during exercise in the environment with 65 ± 5% relative humidity, as compared to 35 ± 5% relative humidity.
Conclusion: These results indicated that cardiorespiratory function in children with asthma and healthy children were different. Cardiorespiratory responses to exercise in children are influenced by environmental conditions such as humidity, so that humidity has a negative impact on the duration of the activity and load on the heart muscle.
M Kachooei, A Fathi-Ashtiani, Volume 20, Issue 12 (3-2016)
Abstract
Background & aim: Eating disorders (EDs) are severe mental disorders which typically occur during young adulthood and are associated with high mortality. On the other hand, the prevalence of EDs has increased in recent years. Accordingly, identifying the predisposing factors of EDs is essential, which can be taken into account in developing interventional programs.The aim of the present research was to investigate the relationship of difficulties in emotion regulation and impulsivity with eating disorder symptoms.
Method: The research method used in the present study was correlation. A total number of 340 women from Tehran general population in 2015 participated in the study by convenient sampling method. The research instruments were Eating Disorders Diagnostic Scale (EDDS), Difficulties in Emotion Regulation (DERS), and Barratt Impulsivity Scale (BIS-11). Data was analyzed using Pearson Correlational Analysis and multiple regression analysis.
Results: Findings of the present study revealed that relationship of eating disorder symptoms with total scores of difficulties in emotion regulation (P<0.01) and impulsivity (P<0.01) were significant. Also there are significant relationship between most subscales of difficulties in emotion regulation including Non-acceptance (P<0.01), goals (P<0.01), Impulse (P<0.01), strategies (P<0.01), and clarity (P<0.01) with eating disorder symptoms. In the other hand, attentional impulsivity (P<0.01), motor impulsivity (P<0.01), and non-planning impulsivity (P<0.05) have significant relationship with eating disorder symptoms. The results of multiple regression analysis indicated that both constructs of difficulties in emotion regulation and impulsivity are significant predictors of eating disorder symptoms. In terms of subscales, stepwise regression analysis also indicated that non-acceptance of negative emotions, limited access to effective emotion regulation strategies and attentional impulsivity can predict the eating disorder symptoms.
Conclusion: Overall, according to the results of the present study, it can be concluded that emotion regulation difficulties and impulsivity play a significant role in the etiology and maintenance of disordered eating. Therefore it can be useful to focus on these factors in prevention and treatment of eating disorders. It means that patients with eating disorders require a therapy that addresses adaptive emotion regulation skills and control of impulsive responding. Future studies can explore effectiveness of different emotion regulation & impulse control skills in reducing symptoms.
A Esfahbodi , M Fathie, M Moazami , Gh R Mohammad Rahimi , Volume 21, Issue 6 (9-2016)
Abstract
Background & aim: Breast cancer is the most common type of cancer and the most common cause of death in middle-aged women in developed countries. The results have indicated that sedentariness and hormonal changes increase the risk of breast cancer. The aim of the present study was to evaluate the effect of eight weeks of aerobic training on levels of growth hormone and 17-beta estradiol middle-aged women with breast cancer.
Methods: In the present semi-experimental study, 15 women with breast cancer with the mean age of 44.46±17.15 years, weight (70.53±5.18 kg) and body mass index (27.58±2.18 kg/m2) were selected through available sampling and considered as the experimental group. The exercise program was performed three sessions per week, and every session lasting 40-60 minutes with an intensity of 30%-60% heart rate reserve (HRR) for eight weeks. Growth hormone and beta 17 estradiol levels pre and post aerobic training, 12 hrs of fasting and with 24 hrs of severe Lack of physical activity was measured during of eight weeks. Data were analyzed by paired samples t-test at a significance levels of P<0.05.
Results: The growth hormone levels did not change significantly after eight weeks of aerobic exercise (P=0.447), whereas 17-beta estradiol levels decreased significantly (P=0.000).
Conclusion: It seemed that eight weeks of aerobic exercise could reduce one of the breast cancer markers (17-beta estradiol); so these training are recommended for the improving or prevention of breast cancer.
G Taheri , M Fathi , E Mir, Volume 24, Issue 3 (7-2019)
Abstract
1.Oliveira A, Monteiro A, Jácome C, Afreixo V, Marques A. Effects of group sports on health-related physical fitness of overweight youth: a systematic review and meta-analysis. Scandinavian Journal Of Medicine & Science In Sports 2017; 27(6): 604-11. ##
2.Bray GA. Fructose: should we worry? International Journal of Obesity 2009; 32(S7): S127. ##
3.Bilski J, Teległów A, Zahradnik-bilska J, Dembiński A, Warzecha Z. Effects of exercise on appetite and food intake regulation. Medicina Sportiva 2009; 13(2): 82-94. ##
4.Shabani M, Mohammad-Zadeh M, Azhdari-Zarmehri H. Orexin (hypocretin): a multi-functional hypothalamic peptide. Koomesh 2014;15(3): 275-81. ##
5.Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and g protein-coupled receptors that regulate feeding behavior. Cell 1998; 92(4): 573-85. ##
6.Coleman DL. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 1978; 14(3): 141-8. ##
7.Kirchgessner AL. Orexins in the brain-gut axis. Endocrine Reviews 2002; 23(1): 1-15. ##
8.Chemelli RM, Willie JT, Sinton CM, Elmquist JK, scammell T, lee C, et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 1999; 98(4): 437-51. ##
9.Salehi Omran MT, Jafari S. Association of admission insulin resistance index with early cardiac complications in non diabetic patients with acute coronary syndrome. Journal of Babol University of Medical Sciences(Jbums) 2009; 6(47): 62-6. ##
10.Defronzo RA. Pathogenesis of type 2 diabetes mellitus. Medical clinics 2004; 88(4): 787-835. ##
11.Skrzypski M, le T, Kaczmarek P, Pruszynska-Oszmalek E, Pietrzak P, Szczepankiewicz D, et al. Orexin a stimulates glucose uptake, lipid accumulation and adiponectin secretion from 3t3-l1 adipocytes and isolated primary rat adipocytes. Diabetologia 2011; 54(7): 1841-52. ##
12.Miyasaka K, Masuda M, Kanai S, Sato N, Kurosawa M, Funakoshi A. Central orexin-a stimulates pancreatic exocrine secretion via the vagus. Pancreas 2002; 25(4): 400-4. ##
13.Matsumura K, Tsuchihashi T, Abe I. Central orexin-a augments sympathoadrenal outflow in conscious rabbits. Hypertension 2001; 37(6): 1382-7. ##
14.Martynska l, Wolinska-witort E, Chmielowska M, Bik W, Baranowska B. The physiological role of orexins. Neuro Endocrinology Letters 2005; 26(4): 289-92. ##
15.Abaassi daluee A, Ghanbari niaki A, Fathi R, Hedayati M. The effect of a single session aerobic exercise on plasma ghrelin, gh, insulin and cortisol in non-athlete university male students. Iranian Journal of Endocrinology and Metabolism 2011; 13(2): 197-201. ##
16.Bagheri Nia M, Abedi B. Effect of eight weeks of pilates training on orexin and insulin resistance levels in overweight children. Yafteh 2018; 1(75): E00109. ##
17.Haskell-luevano C, Schaub JW, Andreasen A, Haskell KR, Moore MC, Koerper IM, et al. Voluntary exercise prevents the obese and diabetic metabolic syndrome of the melanocortin-4 receptor knockout mouse. The Faseb Journal 2009; 23(2): 642-55. ##
18.Mir E, Fathei M, Sayeedi MM, Hejazi K. The effect of eight weeks combined training (aerobic-resistance) on homocysteine, c-reactive protein and lipid profile in inactive elderly men. Medical Journal of Tabriz University of Medical Sciences & Health Services 2015; 36(6): 80-6. ##
19.Abdolmaleki Z, Saleh SB, Bahram A, Abdolmaleki F. Validity and reliability of the physical self-description questionnaire among adolescent girls. Journal of Applied Psychology 2011; 4(16): 42-55. ##
20.Bonora E, Formentini G, Calcaterra F, Lombardi S, Marini F, Zenari L, et al. Homa-estimated insulin resistance is an independent predictor of cardiovascular disease in type 2 diabetic subjects: prospective data from the verona diabetes complications study. Diabetes Care 2002; 25(7): 1135-41. ##
21.Alizadeh AA, Rahmani-nia F, Mohebbi H, Zakerkish M. Effects of eight weeks aerobic exercise on plasma levels of orexin a, leptin, glucose, insulin, and insulin resistance in males with type 2 diabetes. Iranian Journal of Diabetes and Obesity 2015; 7(2): 62-8. ##
22.James MH, Campbell EJ, walker FR, Smith DW, Richardson HN, Hodgson DM, et al. Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats. Frontiers in Behavioral Neuroscience 2014; 8: 244. . ##
23.Wu H, Xia FZ, Xu H, Zhai H, Zhang MF, Zhang HX, et al. Acute effects of different glycemic index diets on serum motilin, orexin and neuropeptide y concentrations in healthy individuals. Neuropeptides 2012; 46(3): 113-8. . ##
24.Ouedraogo R, Näslund E, Kirchgessner AL. Glucose regulates the release of orexin-a from the endocrine pancreas. Diabetes 2003; 52(1): 111-7. . ##
25.Wu T, Gao X, Chen M, Van Dam R. Long-term effectiveness of diet-plus-exercise interventions vs. Diet-only interventions for weight loss: a meta-analysis. Obesity Reviews 2009; 10(3): 313-23. . ##
26.O'neill HM. Ampk and exercise: glucose uptake and insulin sensitivity. Diabetes & metabolism Journal 2013; 37(1): 1-21. . ##
27.Messina G, Di bernardo G, Messina A, Dalia C, Chieffi S, Galderisi U, et al. Brief exercise enhances blood hypocretin-1 in sedentary men. Journal of Sports Medicine & Doping Studies 2014; 4: 149. . ##
28.Butterick TA, Billington CJ, Kotz CM, Nixon JP. Orexin: pathways to obesity resistance? Reviews in Endocrine and Metabolic Disorders 2013; 14(4): 357-64. . ##
29.Sundarrajan L, Unniappan S. Small interfering RNA mediated knockdown of irisin suppresses food intake and modulates appetite regulatory peptides in zebrafish. General and comparative endocrinology. 2017;252:200-8. . ##
30.Bijeh N, Hejazi K. The effect of aerobic exercise on levels of HS-CRP, insulin resistance index and lipid profile in untrained middle-aged women. Razi Journal of Medical Sciences. 2018 Jan 15;24(10):1-1. . ##
31.Ho SS, Dhaliwal SS, Hills AP, Pal S. The effect of 12 weeks of aerobic, resistance or combination exercise training on cardiovascular risk factors in the overweight and obese in a randomized trial. Bmc Public Health 2012; 12(1): 704. . ##
32.Saremi A, Shavandi N, Mohammadpour K. Effects of 8 weeks aerobic training with omega-3 supplementation on inflammatory responses in type 2 diabetic patients. Payesh 2015; 14: 1. . ##
33.Oki K, Yamane K, Kamei N, Nojima H, Kohno N. Circulating visfatin level is correlated with inflammation, but not with insulin resistance. Clinical Endocrinology 2007; 67(5): 796-800. . ##
34.Smith JK, Dykes R, Douglas JE, Krishnaswamy G, Berk S. Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease. Jama 1999; 281(18): 1722-7. . ##
35.Church TS, Barlow CE, Earnest CP, Kampert JB, Priest EL, Blair SN. Associations between cardiorespiratory fitness and c-reactive protein in men. Arteriosclerosis, Thrombosis, and Vascular Biology 2002; 22(11): 1869-76. . ##
36.Christopherson J, Sumer V, Kirkendall D, Jones MA. Effects of exercise detraining on lipid storage in rats. Transactions of the Iillinois State Academy of Science 1999; 92(3): 203-9.
37.Kodama S, Miao S, Yamada N, Sone H. Exercise training for ameliorating cardiovascular risk factors-focusing on exercise intensity and amount. International Journal of Sport and Health Science 2006; 4(2): 325-38. . ##
38.Hosseini k, Attarnejad Z, hosseini HA. A comparison of the effects of two aquatic exercise sessions with different duration on adiponectin and insulin resistance in women with type 2 diabetes. Journal of Sabzevar University of Medical Sciences 2014; 20: 4. . ##
39.Kadoglou NP, Vrabas IS, Kapelouzou A, Lampropoulos S, Sailer N, Kostakis A, et al. The impact of aerobic exercise training on novel adipokines, apelin and ghrelin, in patients with type 2 diabetes. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research 2012; 18(5): cr290. . ##
 Armaghane-danesh, Yasuj University of Original Article
Medical Sciences Journal (YUMSJ)
Changes in Orexin A Serum Level, Insulin Resistance and Anthropometric Indices in Overweight Women after Six Weeks of Aerobic Training
Taheri G1, Fathi M2*, Mir E2
[1]Department of Sport Physiology, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran, 2 Department of Sport Physiology, Ferdowsi University of Mashhad, Mashhad, Iran
Received: 10 Dec 2018 Accepted: 12 May 2019
Abstract
Background & aim: Orexin is an orexigenic peptide present in the form of A and B in the blood. Orexin neurons respond to a number of metabolic signals that indicate the body's energy status. The present study was carried out to evaluate the effect of six weeks of aerobic training on orexin level, insulin resistance and anthropometric indices in overweight women.
Methods: In the present quasi-experimental study, the statistical population consisted of overweight and inactive women in Bojnourd, Iran,, aged 45-65 years, and BMI 26-29 kg/m2. Twenty-four eligible individuals were randomly divided into two groups of control and exercise. The exercise included aerobic training (with intensity of 60-70% of maximum heart rate reserve). The exercise performed three times per week for six weeks.
Results: The six weeks of aerobic training increased the orexin A level and decreased insulin, glucose, insulin resistance index, weight, BMI, WHR and fat percentage in interventional group. But in control group none of these variables changed significantly after six weeks(P<0.05).
Conclusion: The six weeks of aerobic training increased the orexin A level, decreased insulin resistance and improves anthropometric indices in overweight women. Therefore, obese women are recommended to use these exercises as a preventive method for future diabetes and cardiovascular diseases.
R Rezaei , M Fathi , Volume 24, Issue 5 (12-2019)
Abstract
Background & aim: MYH7 and MYH7β genes play important roles in cardiac function. Endurance activity, on the other hand, challenges the structure and function of the heart. The aim of the present study was to determine and evaluate the effect of 14 weeks of endurance training on MYH7 and MYH7β gene expression and left ventricular structural changes in male Wistar rats.
Methods: In the present experimental research, 14 rats weighing 113±20gr under controlled conditions (temperature, light and dark cycle, free access to food and water) were retained. After exposure (231±24g), they were randomly divided into control (7) and experimental (7) groups. The experimental group completed a program (30 m/min, 50 min/session, 6 sessions/week for 14 weeks) on the treadmill and then anesthetized and described 48 hours after the last training session with the control group. Then their hearts and their left ventricles were removed and MYH7 and MYH7β gene expression levels were measured using Real time-PCR. Data were analyzed using independent and dependent t-tests.
Results: The results of the present study indicated that cardiac weight gain and MYH7 and MYH7β gene expression were increased in the exercise group, meaning that endurance exercise significantly increased the heart to body weight ratio in the experimental group compared to the control group. Expression of MYH7 and MYH7β genes was not significantly higher in the experimental group (p = 0.005) (p = 0.001).
Conclusion: It seemed that the endurance training induced remodeling which was indicated by hypertrophy and it coincided with increasing of MYH7 and MYH7b genes expression. This may be part of an improvement in cardiac function due to exercise activity due to increased expression of these genes
H Rostami, M Fatehi , A Fathi, A Moradi, Volume 25, Issue 0 ( Number 1, Corona Special Issue 2021)
Abstract
Background & aim: Covid-19 is a new virus that the human immune system is not immune to. In addition to physical problems, the virus also has negative psychological consequences. The aim of the present study was to compare resilience, happiness and lifestyle in patients with covid-19 and healthy individuals.
Methods: This descriptive-analytical case study was conducted in 2020. The statistical population of the study was all patients with coronavirus hospitalized and healthy patients in Al-Ghadir Hospital in Tabriz in April 2020. Thirty patients with Covid-19 were hospitalized and 30 healthy individuals were selected from the hospital with accessibility and Connor and Davidson resilience, Oxford happiness and Miller and Smith lifestyle questionnaires were administered among them. The collected data were analyzed using multivariate analysis of variance and Levin test.
Results: The mean and standard deviation of reproductive scores in patients with Covid -19 was 71/90 ±22/35 and in healthy people was 96/70 ±17/20; The mean and standard deviation of happiness scores in patients with Covid -19 was 21/40±3/81 and in healthy people 23/33±2/80 and the mean and standard deviation of lifestyle scores in patients with Covid -19 equal to 68/53 ± 9/78 and in healthy people was 73/43±9/36. The results of multivariate analysis of variance showed that the scores of resilience, happiness and lifestyle were lower among people with Quaid-19 than healthy people (P <0.05).
Conclusion: Given the increasing prevalence of coronary heart disease, it is better for the country's authorities to take psychological measures to increase resilience, happiness and a healthy lifestyle in patients with Covid-19 who have been exposed to mental and emotional disorde
S Rahmani Chegni , M Fathi , R Mohammad Hosseini Sarvak , Volume 25, Issue 0 ( Number 1, Corona Special Issue 2021)
Abstract
Background & aim: The prevalence of coronavirus worldwide has led to severe limitations including reduced physical activity. The aim of the present study was to determine the effect of a period of inactivity due to the outbreak of coronavirus on the body composition and maximum oxygen consumption of adolescents.
Methods: In the present quasi-experimental study conducted in 2020, 178 male adolescents (mean age 13.85 05 0.057 years) participated voluntarily. Indicators such as height, weight, body mass index and maximum oxygen consumption were measured in two time intervals with an interval of 6 months as pre-test and post-test. Cooper test was used to determine the maximum aerobic capacity. After data collection, first the normality of the data was calculated using the K-s test and then the pre-test data were compared with the post-test using the dependent t-test. Correlated t-test was used to analyze the mean values of pre-test and post-test data.
Results: The results of the present study indicated that lifestyle changes due to the spread of coronavirus caused the mean weight index to change from (50.34 ± 0.79) to (54.25 ± 0.89) and body mass. Change from (19.64 ± 0.26) to (20.26 ± 0.29) and the maximum oxygen consumption likewise changes from (31.04 ± 0.29) to (30.12 ± 0.27). From these effects, it could be understood that COVID-19 causes a significant increase in body mass index (p = 0.001), weight (p = 0.001) and also a significant decrease in maximum oxygen consumption (p = 0.032).
Conclusion: According to the results of the present study, it can be noted that a six-month period of inactivity caused by the outbreak of coronavirus causes changes in body composition and therefore threatens health.
P Karimi Sani , دکتر Sh Zeinali , Sm Tabatabai , H Rostami , A Fathi, Miss P Alamshahi Vayqan, Volume 25, Issue 2 (5-2020)
Abstract
Background & aim: Diabetes is as a chronic disorder, which produce lots of limitation in patients' activities and psychological quality. The aim of the present study was to investigate the efficacy of cognitive-behavioral therapy based on Lazarus's multimodal approach to psychological weakness and thoughts fusion among diabetic patients with wounds.
Methods: The present study was a semi-experimental (pre-test, post-test) with a control and experimental group. The statistical population of study consisted of 50 diabetic patients with wounds in Tabriz Sina Hospital, 24 patients with Purposive sampling selected and randomly divided into two experimental and control groups (each group was 12). The experimental group participated in group sessions for 8 sessions of 120 minutes, while the control group did not receive any intervention. Subjects in both experimental and control groups were assessed with the Minnesota Multiplier Questionnaire (MMPI) Questionnaire (Pt sub-scale) and Thought Fusion Inventory (TFI) before and after treatment. Data were analyzed by descriptive statistics (such as mean and standard deviation), ANCOVA and MANCOVA.
Results: Results indicated that there were significant differences in post-test mean scores of experimental and control groups and cognitive behavior therapy could significantly reduce psychological weakness (F=41/138, p=0.01) and increase thought fusion (F=9/306, P<0.007).
Conclusion: Cognitive behavioral therapy with changing maladaptive thought and helping to accept disease, resulted in behavior change in diabetic patients.
M Azimpour, M Fathi, O Dezfulian, Volume 26, Issue 3 (7-2021)
Abstract
Armaghane-danesh, Yasuj University of Original Article
Medical Sciences Journal (YUMSJ)
The Effect of Eight Weeks of Royal Jelly Consumption on Some of Apoptotic Indicators in Trimethyltin-Induced Alzheimer's Mice
Azimpour M, Fathi M*, Dezfulian O
Department of Physical Education, Lorestan University, Khorramabad, Iran
Received: 05 Sep 2020 Accepted: 10 Oct 2020
Abstract:
Background & aim: Given that Royal Jelly contains compounds that have beneficial effects on the central nervous system and neural functions, therefore, the aim of this study was to determine and evaluate the effect of Royal Jelly consumption on apoptotic indices in trimethyltin model of Alzheimer's disease.
Methods: In the present experimental study conducted in fall of 2018, 32 male Sprague-Dawley rats were included in the study. Twenty-four of them were induced by Alzheimer's induction by trimethyltin. The rats were then randomly divided into four groups: healthy last week, victim control last week, sham and royal jelly. The expression of P53, BAX, BCL-2 genes were measured by Real Time PCR technique. Data analysis was performed by Manova test and post hoc Scheffe at the significant level P<0.05 using SPSS software version 20.
Results: The findings of the present study indicated that the dependent variable P53 in the last week Alzheimer's group was more than the healthy groups in the last week and gel. Moreover, the dependent variable P53 in the sham group was more than the healthy groups in the last week and the gel. In the healthy group, the last week was less than sham and Alzheimer's last week. BCL-2 in the gel group was more than sham and healthy last week and Alzheimer's last week and in the healthy group last week was more than sham and Alzheimer's last week.
Conclusion: Trimethylmethine administration may be involved in selective neuronal death and mitochondrial apoptotic pathways in neurodegenerative disorders, and royal jelly supplementation may be used as an inhibitor of the internal pathway of apoptosis and to enhance neural function and neuronal regeneration in the present model .
M Fathi , S Ahmadabadi , Volume 26, Issue 4 (9-2021)
Abstract
Background & aim: The increase of myoD gene expression is the characteristic of activation and proliferation of satellite cells due to induced stimulus in skeletal muscle. But it seems the fast and slow skeletal muscle response and the appearance of this marker due to stimulus are not similar. Accordingly, the present study aimed to evaluate the effect of endurance training on myoD gene expression in fast and slow skeletal muscle in Wistar male rats.
Methods: In the present study conducted in 2020, 14 rats (weight 234±24g) provided from Pasteur Institute and housed under natural conditions (temperature, light/dark (12-h) cycle, with ad Libitum access to food and water). The rats randomly divided to two groups experimental (n=7) and control (n=7); the experimental group performed an endurance training program (30 m/min, 50 min, 6 sessions per week for 14-weeks) on a motorized treadmill, and 48 hours after the end of the last session of endurance activity with the control group were anesthetized and sacrificed, then the soleus and extensor digitorum longus (EDL) muscles were removed. Real-time RT-PCR was used to determine if expression levels of myoD gene. To conclude, the data were analyzed by independent t-test.
Results: endurance training induced a significant increase (p=0.022) in EDL myoD gene expression; correspondingly, this modification was observed in soleus muscles (p=0.001)
Conclusion: it appeared that endurance training increased the myoD gene expression in soleus (slow-twitch muscle) and EDL (fast-twitch muscle).
M Tarhani , M Fathi, M Rahmati , Volume 27, Issue 1 (3-2022)
Abstract
Background & aim: Primary dysmenorrhea is one of the most common disorders in adolescent girls. Exercise has positive effects on women with primary dysmenorrhea. The aim of the present study was to evaluate the effect of aerobic exercise with different intensity (low, medium and high) on pain, menstrual symptoms and quality of life in adolescent girls with primary dysmenorrhea.
Methods: This is a quasi-experimental study, the statistical population consisted of 60 sedentary adolescent girls with severe and moderate dysmenorrhea who were randomly divided into three training groups and a control group. Subjects completed a menstrual symptom questionnaire to assess dysmenorrhea symptoms. The training protocol of the sports groups was performed three times a week. The VAS questionnaire was used to assess the amount of pain and the menstrual distress questionnaire and the abbreviated form of the WHOQOL questionnaire were used to assess menstrual symptoms and quality of life, respectively. Data were analyzed using analysis of variance, dependent t-test and Tukey's post hoc tests.
Results: The results indicated that there was a difference between the three intensities of aerobic exercise on pain (p = 0.133), duration of pain (p = 0.19) and menstrual symptoms (p = 0.239) in adolescent girls with primary dysmenorrhea. No significance was observed. In contrast, low-intensity aerobic exercise had a greater effect on improving the quality of life of adolescent girls with primary dysmenorrhea (p = 0.001).
Conclusion: The results of the present study revealed that low-intensity aerobic exercise had a positive effect on the quality of life of girls with primary dysmenorrhea, which lead to its improvement, although high-intensity exercise was correspondingly effective in reducing the duration of dysmenorrhea.
N Rouzbayani , M Fathi , M Rahmati , Volume 27, Issue 4 (7-2022)
Abstract
Background & aim: Decreased bone density, especially in women, is a health risk factor; therefore, the aim of the present study was to investigate the effect of a resistance training course with vitamin D supplementation on bone absorption markers in girls.
Methods: The participants of the present semi experimental study were 24 non-athlete girls in Boroujerd (mean age 21.6 ± 2.04 years, mean height 155 ± 5.5 cm and average weight 64.13 64 4.9 kg) who participated voluntarily and were randomly divided into four groups of six (resistance training, vitamin D intake, resistance training with vitamin D intake and control group). Resistance training consisting of eight weeks (three one-hour sessions per week) was performed in accordance with the principle of overload. The participants were given Vitamin D supplementation for eight weeks (once a week) using vitamin D tablets (8 pearl IU50000) with 300 ml of water. Blood samples were taken 48 hours before the beginning of the protocol and 48 hours after the end of the last session to measure the serum concentrations of parathyroid hormone and calcitonin. ANCOVA and Bonferroni post hoc test were used to analyze the hypotheses.
Results: The results indicated that after eight weeks of resistance training, as well as eight weeks of resistance training with vitamin D, a significant increase in serum calcitonin concentration (p=0.001) and a decrease in serum parathyroid hormone concentration (p=0.001) Occurred.
Conclusion: It seems that resistance activity and vitamin D consumption increases calcitonin and decreases Parathormone in sedentary girls, which probably has a positive effect on bone mass.
F Nasiri, M Fathi , R Rezaei , M Kadkhodai , Volume 29, Issue 4 (7-2024)
Abstract
Background & aim: stroke causes damage to the sensory and motor systems and motor and cognitive disabilities due to impaired blood supply to an area in the brain. The aim of the present study was to investigate the effect of exercises at home with functional overload on acute stroke patients.
Methods: In the present semi-experimental study conducted in 2024, as a pre-test and post-test with intervention and control groups, the statistical population included stroke patients referred to the clinic of Shohdai Eshair Hospital in Khorramabad. The statistical sample included 24 acute stroke patients who were randomly divided into two groups (intervention and control). In two stages of pre-test and post-test (after 12 weeks of training), leaf balance test, measurement of functional independence, dolly walking test and electromyography examination of anterior tibialis muscle and quadriceps femoris were performed in both groups.The collected data were analyzed using independent t and Kolmogorov-Smirnov statistical tests.
Results: The balance examination with a significant level (p = 0.0001), in the walking test with a significant level (p = 0.0001) and in the functional independence test with a significant level (0.0001) p=0/) in the experimental group, the situation was better. Electromyography examination of quadriceps muscle nerve with a significant level (p=0.01) and anterior tibialis muscle nerve with a significant level (p=0.01) revealed that the muscle amplitude of the control group was better.
Conclusion: The results of the present study indicated that in addition to clinical exercises, home-based exercises using a weight or weight cuff improve independent performance, walking, and balance in acute stroke patients, which was associated with positive changes in muscle electromyography.
Iman Fathi, Vahid Ghanbari Mazidi, Zia Navidi, Volume 30, Issue 3 (4-2025)
Abstract
Background & aim: Obesity is widely recognized as a significant health concern due to its association with various diseases, including fatty liver disease. This study aimed to examine the effects of two types of exercise—aerobic and resistance training—combined with cinnamon supplementation on the levels of liver inflammatory markers in obese subjects.
Methods: Following a two-month obesity induction period using a high-fat diet, 42 male Wistar rats were divided into seven groups: control, obese control, obese cinnamon, obese aerobic exercise, obese resistance exercise, obese aerobic exercise with cinnamon, and obese resistance exercise with cinnamon. The supplement groups received 200 mg/kg of cinnamon extract daily. The exercise groups performed their respective training protocols for four weeks, four days per week. The control and obese control groups received no intervention. To account for dietary effects, all rats were maintained on a high-fat diet throughout the one-month training period. After confirming the normality of the data and homogeneity of variances, a one-way ANOVA was used to compare the groups at a significance level of P ≤ 0.05.
Results: The results showed a significant reduction in the levels of alanine aminotransferase (P = 0.011), aspartate aminotransferase (P = 0.025), and alkaline phosphatase (P = 0.018) in the aerobic exercise group compared to the obese control group. Similarly, the resistance training group exhibited a significant decrease in alanine aminotransferase (P = 0.005), aspartate aminotransferase (P = 0.043), and alkaline phosphatase (P = 0.041) levels compared to the obese control group. However, no significant differences were observed between the aerobic and resistance training groups.
Conclusion: It appears that in individuals who are dealing with obesity and overweight, engaging in aerobic or resistance exercises along with cinnamon supplementation may help improve indicators of liver inflammation.
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