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Investigating the changes in the levels of liver inflammatory markers to two types of aerobic and resistance training combined with the consumption of cinnamon supplements in obese rats
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Iman Fathi1   , Vahid Ghanbari Mazidi2 , Zia Navidi3 |
1- Vali-e-Asr University of Rafsanjan , imanfathi@gmail.com
2- Vali-e-Asr University of Rafsanjan
3- Rafsanjan University of Medical Sciences |
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Abstract: (331 Views) |
Background & aim: Obesity is widely recognized as a significant health concern due to its association with various diseases, including fatty liver disease. This study aimed to examine the effects of two types of exercise—aerobic and resistance training—combined with cinnamon supplementation on the levels of liver inflammatory markers in obese subjects.
Methods: Following a two-month obesity induction period using a high-fat diet, 42 male Wistar rats were divided into seven groups: control, obese control, obese cinnamon, obese aerobic exercise, obese resistance exercise, obese aerobic exercise with cinnamon, and obese resistance exercise with cinnamon. The supplement groups received 200 mg/kg of cinnamon extract daily. The exercise groups performed their respective training protocols for four weeks, four days per week. The control and obese control groups received no intervention. To account for dietary effects, all rats were maintained on a high-fat diet throughout the one-month training period. After confirming the normality of the data and homogeneity of variances, a one-way ANOVA was used to compare the groups at a significance level of P ≤ 0.05.
Results: The results showed a significant reduction in the levels of alanine aminotransferase (P = 0.011), aspartate aminotransferase (P = 0.025), and alkaline phosphatase (P = 0.018) in the aerobic exercise group compared to the obese control group. Similarly, the resistance training group exhibited a significant decrease in alanine aminotransferase (P = 0.005), aspartate aminotransferase (P = 0.043), and alkaline phosphatase (P = 0.041) levels compared to the obese control group. However, no significant differences were observed between the aerobic and resistance training groups.
Conclusion: It appears that in individuals who are dealing with obesity and overweight, engaging in aerobic or resistance exercises along with cinnamon supplementation may help improve indicators of liver inflammation. |
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| Keywords: liver inflammatory factors, aerobic training, resistance training, ALT, AST, ALP |
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Type of Study: Research |
Subject:
Sport Physiology
Received: 2024/12/17 | Accepted: 2025/02/24 | Published: 2025/05/6
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